How science goes wrong? we’re improving!


Fraud, shoddy and sloppy science, conflicts of interest… Who said a science career is boring? When I write on these topics I sometimes have the feeling that I am doing science more harm than good; am I doing science a favor by showing its weaknesses and caveats? The answer still remains yes, for I believe that we need problems need to be identified before you can act on them. This is also the theme of this post: What is all being done on these topics in the last couple of days. A point by point list:

  • AllTrials: The AllTrials initiative which I support is going into its next round.Pharmaceutical companies are opening up (LEO, GSK), there are hearings in brussels and the debate in Medical journals (especially the BMJ, as one of the founders of AllTrials) is going on. Great stuff!
  • PubMed commons (a commenting system in PubMed, as a new post publication peer review) got online. It’s still a trial, but boy this is cool. I love its punchline: “A forum for scientific discourse”.
  • We organised a try out of our ‘on being a scientist’ workshop on which i wrote earlier this post. IN this post i say that is if going to be a LUMC workshop, but this changed to a workshop for all starting PhD students from the university Leiden, thus including all faculties. I am truly exciting and it our first run in november works out, this workshop might even become part of the official PhD education program of the university Leiden. The economist published a coverstory on How science goes wrong. It tells how science, peer review, statistical false positives etc work. It is a good read, especially when you are interested in science as a social process. Some remarks can be made: it’s not all that bad because scientist tend to be familiar with how the system works… the system might not be perfect, but it is at the moment the best we can do… luckily there are ways to get better, ways that are also discussed in the article.It is good that the economist and other media shares these concerns, because now this might up to build to critical mass to really change some of the weak points in the system. I thought about using the graph published next to the paper, but once I discovered the animated version of the graph i fell in love. See for yourself below. (PS false positives: another reason why not only to rely on statistical testing!)
  •  – edit: i changed the title of the pot… the first title was a bit pretentious –